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Rejuran in Seoul

Medically reviewed by Kim Yunseok, CEO / Representative Director · Reviewed by our editorial team

Rejuran is one of the most requested skin boosters for patients exploring Rejuran Seoul options, thanks to its simple concept: a purified salmon DNA extract, technically called polynucleotide, injected into the skin to support cellular repair. At DERNA Clinic, located in Seocho-gu, this treatment is offered in several formats to suit different skin concerns and comfort levels.

What it is

Rejuran belongs to the booster category of injectable treatments. Rather than adding volume like a filler, it works at the tissue level, encouraging the skin's own repair processes. The active ingredient, salmon-derived DNA, has been studied for its role in supporting collagen activity and improving skin texture over time. DERNA Clinic offers two main lines: Rejuran Healer, available in 2cc or 4cc doses, and Rejuran HB+, also in 2cc or 4cc, both administered by hand injection. There is also a version formulated specifically for the delicate skin around the eyes. Choosing between these depends on the area treated, skin condition, and the practitioner's assessment during consultation.

Who it suits

People considering Rejuran in Seoul often have concerns such as dull or tired-looking skin, fine lines, uneven texture, or a loss of skin elasticity that comes with age or sun exposure. It is also chosen by patients who want a subtle, gradual improvement rather than an immediate change in facial shape. Because it is a skin-quality treatment rather than a volumizing one, it tends to appeal to those who prefer a natural-looking result built up over a series of sessions. Some patients combine it with other skincare or booster treatments, though any combination should be discussed directly with the treating doctor.

Who should avoid it

Rejuran is not suitable for everyone. Patients with active skin infections, open wounds, or inflammatory skin conditions in the treatment area are generally advised to wait until the skin has healed. Anyone with a known allergy to fish products or previous reactions to polynucleotide injections should raise this during consultation, since the active ingredient is derived from salmon. Pregnant or breastfeeding patients, those with bleeding disorders, or people currently on blood-thinning medication should also disclose this before treatment. As with any injectable, a medical consultation is required so the doctor can review medical history and decide whether the treatment is appropriate for that individual.

How the session goes

A typical visit starts with a consultation where the doctor examines the skin and discusses which product and dosage may be suitable. Depending on the area, a topical numbing cream may be applied beforehand to reduce discomfort. The treatment itself involves a series of small injections placed across the target area by hand, a technique that allows the practitioner to adjust depth and spacing according to the skin's needs. Sessions are usually completed within thirty minutes to an hour, though timing can vary depending on the area treated and the number of points injected. Most patients are able to leave shortly after the appointment.

Downtime and recovery

Some redness, mild swelling, or small bumps at the injection sites are common in the first day or two. These effects are usually temporary and tend to settle within a few days, though individual healing speed varies. Makeup can often be applied once any pinpoint marks have resolved, but patients should check with their doctor about timing. Sun exposure should be minimized in the days following treatment, and gentle skincare is generally recommended while the skin recovers. Results are not immediate in most cases; skin texture improvements tend to build gradually, and a series of sessions spaced a few weeks apart is often suggested rather than a single visit. As results vary from person to person, it is difficult to predict an exact timeline or outcome in advance.

Pricing

Rejuran at DERNA Clinic is priced from 250,000 KRW. This figure serves as a starting reference; the final cost can depend on the specific product line chosen, whether 2cc or 4cc is used, and whether an eye-area option or combination treatment is added. VAT and consultation fees may also apply and are best confirmed directly with the clinic before booking. Patients traveling from abroad for Rejuran Seoul treatment should request a written quote during their consultation to avoid confusion about the final total.

ItemDetail
ClinicDERNA Clinic
AddressB2F, 17 Seocho-daero 77-gil, Seocho-gu, Seoul
HoursMon–Sun 10:00–22:00 (Wednesday 10:00–11:00 reserved for staff training, no patients)
Phone+82 2-3478-8970
Email[email protected]

Safety

Rejuran is administered by the clinic's medical doctors, and a consultation precedes every treatment to assess suitability. The clinic's team includes doctors with varied backgrounds, including otolaryngology and general medical training, and the CEO is an orthopedic surgeon. As with any injectable procedure, there are possible side effects, including bruising, temporary swelling, or, rarely, an allergic reaction. No treatment can be guaranteed to work identically for every patient, and results should be understood as variable rather than fixed. Patients are encouraged to disclose their full medical history, ask questions about the specific product being used, and follow aftercare instructions provided by the clinic to support a smoother recovery.

Frequently asked questions

How many sessions of Rejuran are typically needed?

Many patients undergo a series of three sessions spaced a few weeks apart, though the exact plan depends on skin condition and the doctor's recommendation.

Is Rejuran painful?

Most patients describe mild discomfort rather than significant pain, and topical numbing cream can be applied beforehand to improve comfort.

Can Rejuran be combined with other treatments?

It is sometimes combined with other boosters or skin treatments, but any combination should be reviewed and approved by the treating doctor first.

How long do results from Rejuran last?

Results are not permanent and vary between individuals; effects on skin texture typically develop gradually and may fade over time, which is why repeat sessions are common.

Do I need a consultation before booking Rejuran in Seoul?

Yes, a consultation is required so the doctor can review your medical history, skin condition, and expectations before deciding on the appropriate product and dosage.

General information for international patients. Not medical advice. Individual results vary; consult a qualified physician.

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